VThunter

a database for single-cell screening of virus target cells in animal kingdom

Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

Foot-and-mouth disease virus

Family: Picornaviridae

Receptor: ITGB6

Receptor ITGB6 information

Summary: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants.? [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0035	2021.04	10X Genomics	Duodenum	Normal	1482	Link
Vthunter_0036	2021.04	10X Genomics	Esophagus	Normal	24581	Link
Vthunter_0037	2021.04	10X Genomics	Heart	Normal	12958	Link
Vthunter_0038	2021.04	10X Genomics	Kidney	Normal	4481	Link
Vthunter_0039	2021.04	10X Genomics	LargeIntestine	Normal	3328	Link
Vthunter_0040	2021.04	10X Genomics	Liver	Normal	5694	Link
Vthunter_0041	2021.04	10X Genomics	Lung	Normal	13720	Link
Vthunter_0042	2021.04	10X Genomics	Spleen	Normal	3207	Link
Vthunter_0043	2021.04	10X Genomics	Stomach	Normal	12485	Link

Featureplot of receptors

mRNA expression of ITGB6 in human tissues [NCBI]

Expression: Biased expression in lung (RPKM 25.8), urinary bladder (RPKM 17.2) and 12 other tissues

Protein expression of ITGB6 in human tissues [Proteinatlas]